…s patients ON and OFF levodopa, with and without DBS (Wiest et…
This dataset contains multimodal recordings from 12 patients with idiopathic Parkinson's disease who have bilateral subthalamic deep brain stimulation (Medtronic Percept PC). Recordings were made after overnight withdrawal of dopaminergic medication with stimulation OFF, during sitting, standing, walking through a narrow corridor, walking with self-initiated stops, and walking with a dual task. Signals include bipolar subthalamic local field potentials, 48-channel scalp EEG with surface EMG, and inertial sensor kinematics, supporting study of freezing of gait.
…score - Parkinson's disease duration - Levodopa equivalent daily dose (LEDD) - Resting-state…
EEG dataset from a reinforcement learning task performed by 28 patients with Parkinson's disease and 28 matched healthy controls. The task included volitional and instructed choices. Patients were tested twice, ON and OFF dopaminergic medication, one week apart, while controls were tested once. Accelerometer data from the most tremor-affected hand were also recorded.
…collected, including: - **Demographic data** - **LEDD** (Levodopa Equivalent Daily Dose) - a measure of…
Intraoperative recordings from 18 patients with Parkinson's disease undergoing subthalamic nucleus (STN) deep brain stimulation surgery, combining macroelectrode LFP from STN trajectories with subdural strip recordings over anterior and lateral prefrontal cortex. Participants performed a working-memory encoding task, viewing eight sequential digits and remembering only those inside a target shape. This derivative release contains band-passed, notch-filtered, downsampled and re-referenced iEEG data in BIDS format with trial-level events.
Intraoperative subthalamic nucleus (STN) local field potential recordings from patients with Parkinson's disease undergoing deep brain stimulation implantation at Duke University Medical Center. Patients performed a self-paced balloon analogue risk task (BART) while LFPs were recorded from single microelectrodes or 32-channel microwire arrays. This derivative repackages the LFP, decimated to 200 Hz, into BIDS iEEG format with behavioural and artifact-censoring events (17 recordings from 14 patients, about 4.3 h).
EEG recordings from 25 patients with Parkinson's disease and 25 matched controls during resting state (eyes open and eyes closed) and a three-stimulus auditory oddball task. Patients were recorded twice, one week apart, once ON and once OFF dopaminergic medication, while controls were recorded once. Accelerometer data from the most tremor-affected hand are included, along with metadata spreadsheets and code to reproduce the associated paper.
This dataset contains simultaneous magnetoencephalography (MEG) and subthalamic nucleus local field potential (STN LFP) recordings from externalized deep brain stimulation (DBS) patients with Parkinson's disease. Recordings were acquired with and without dopaminergic medication during rest, static forearm extension (hold), and self-paced fist-clenching (move). The project aimed to characterize basal ganglia-cortex loop neurophysiology and how it is modulated by movement and medication.
Local field potential recordings from externalised octopolar deep brain stimulation leads in 7 patients with isolated idiopathic (cranio)cervical dystonia (12 hemispheres), spanning the subthalamic nucleus, rostral zona incerta and ventrolateral thalamus. Recordings were made 4-7 days after surgery, off medication, during stimulation delivered through the lead. Some patients also had scalp EEG, neck muscle EMG and accelerometer recordings. This derivative release is a BIDS repackaging of the original data at 4096 Hz, with DC offset removed by the original authors.